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Poly(A)-seq: A method for direct sequencing and analysis of the transcriptomic poly(A)-tails

Poly(A) tails at the 3’ end of eukaryotic messenger RNAs control mRNA stability and translation efficiency. Facilitated by various NGS methods, alternative polyadenylation sites determining the 3ʹ-UTR length of gene transcripts have been extensively studied. However, poly(A) lengths demonstrating dy...

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Detalles Bibliográficos
Autores principales: Yu, Fengyun, Zhang, Yu, Cheng, Chao, Wang, Wenqing, Zhou, Zisong, Rang, Wenliang, Yu, Han, Wei, Yaxun, Wu, Qijia, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297374/
https://www.ncbi.nlm.nih.gov/pubmed/32544193
http://dx.doi.org/10.1371/journal.pone.0234696