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A human H1-HBB11-GFP reporter embryonic stem cell line (WAe001-A-2) generated using TALEN-based genome editing
Hemoglobin production during mammalian development is characterized by temporal switches of the genes coding for the α- and β-globin chains. Defects in this controlled process can lead to hemoglobinapathies such as sickle cell disease and β-thalassemia. The ability of human embryonic stem cells (hES...
Autores principales: | Alexeeva, Vera, Aydin, Iraz T., Schaniel, Christoph, Stranahan, Alec W., D’Souza, Sunita L., Bieker, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297435/ https://www.ncbi.nlm.nih.gov/pubmed/32413789 http://dx.doi.org/10.1016/j.scr.2020.101837 |
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