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Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

Comprehensive sequencing approaches have allowed for the identification of the most frequent contributors to cancer, known as drivers. They have also revealed a class of mutations in understudied, infrequently altered genes, referred to as “long tail” (LT) drivers. A key challenge has been to find c...

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Detalles Bibliográficos
Autores principales: Elman, Jessica S., Ni, Thomas K., Mengwasser, Kristen E., Jin, Dexter, Wronski, Ania, Elledge, Stephen J., Kuperwasser, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297508/
https://www.ncbi.nlm.nih.gov/pubmed/31553912
http://dx.doi.org/10.1016/j.celrep.2019.08.060