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Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
Comprehensive sequencing approaches have allowed for the identification of the most frequent contributors to cancer, known as drivers. They have also revealed a class of mutations in understudied, infrequently altered genes, referred to as “long tail” (LT) drivers. A key challenge has been to find c...
Autores principales: | Elman, Jessica S., Ni, Thomas K., Mengwasser, Kristen E., Jin, Dexter, Wronski, Ania, Elledge, Stephen J., Kuperwasser, Charlotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297508/ https://www.ncbi.nlm.nih.gov/pubmed/31553912 http://dx.doi.org/10.1016/j.celrep.2019.08.060 |
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