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Calling for an exponential escalation scheme in vaccine development for COVID-19

PURPOSE: COVID-19 as a pandemic calls for rapid development of vaccines. METHODS: Here a proposal of a seamless, adaptive, phase 1–3 trial for accelerated vaccine development is described. RESULTS: Starting at 10, the number of vaccinated volunteers would exponentially increase by tenfold at an inte...

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Detalles Bibliográficos
Autor principal: Wehling, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297510/
https://www.ncbi.nlm.nih.gov/pubmed/32548679
http://dx.doi.org/10.1007/s00228-020-02933-w