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Calling for an exponential escalation scheme in vaccine development for COVID-19
PURPOSE: COVID-19 as a pandemic calls for rapid development of vaccines. METHODS: Here a proposal of a seamless, adaptive, phase 1–3 trial for accelerated vaccine development is described. RESULTS: Starting at 10, the number of vaccinated volunteers would exponentially increase by tenfold at an inte...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297510/ https://www.ncbi.nlm.nih.gov/pubmed/32548679 http://dx.doi.org/10.1007/s00228-020-02933-w |