Type I interferon underlies severe disease associated with Junín virus infection in mice

Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever (AHF). The pathogenesis underlying AHF is poorly understood; however, a prolonged, elevated interferon-α (IFN-α) response is...

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Detalles Bibliográficos
Autores principales: Hickerson, Brady T, Sefing, Eric J, Bailey, Kevin W, Van Wettere, Arnaud J, Penichet, Manuel L, Gowen, Brian B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297529/
https://www.ncbi.nlm.nih.gov/pubmed/32452770
http://dx.doi.org/10.7554/eLife.55352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297529/
https://www.ncbi.nlm.nih.gov/pubmed/32452770
http://dx.doi.org/10.7554/eLife.55352

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