Hepatitis C virus exploits cyclophilin A to evade PKR

Counteracting innate immunity is essential for successful viral replication. Host cyclophilins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechanisms are still unclear. Here, we show that hepatitis C virus (HCV) co-opts the host protein CypA to aid evasion...

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Detalles Bibliográficos
Autores principales: Colpitts, Che C, Ridewood, Sophie, Schneiderman, Bethany, Warne, Justin, Tabata, Keisuke, Ng, Caitlin F, Bartenschlager, Ralf, Selwood, David L, Towers, Greg J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297535/
https://www.ncbi.nlm.nih.gov/pubmed/32539931
http://dx.doi.org/10.7554/eLife.52237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297535/
https://www.ncbi.nlm.nih.gov/pubmed/32539931
http://dx.doi.org/10.7554/eLife.52237

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