Predictable properties of fitness landscapes induced by adaptational tradeoffs

Fitness effects of mutations depend on environmental parameters. For example, mutations that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the absence of antibiotic, exemplifying a tradeoff between adaptation to environmental extremes. We develop a mathemati...

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Detalles Bibliográficos
Autores principales: Das, Suman G, Direito, Susana OL, Waclaw, Bartlomiej, Allen, Rosalind J, Krug, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297540/
https://www.ncbi.nlm.nih.gov/pubmed/32423531
http://dx.doi.org/10.7554/eLife.55155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297540/
https://www.ncbi.nlm.nih.gov/pubmed/32423531
http://dx.doi.org/10.7554/eLife.55155

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