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Weighted persistent homology for osmolyte molecular aggregation and hydrogen-bonding network analysis
It has long been observed that trimethylamine N-oxide (TMAO) and urea demonstrate dramatically different properties in a protein folding process. Even with the enormous theoretical and experimental research work on these two osmolytes, various aspects of their underlying mechanisms still remain larg...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297731/ https://www.ncbi.nlm.nih.gov/pubmed/32546801 http://dx.doi.org/10.1038/s41598-020-66710-6 |