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Weighted persistent homology for osmolyte molecular aggregation and hydrogen-bonding network analysis

It has long been observed that trimethylamine N-oxide (TMAO) and urea demonstrate dramatically different properties in a protein folding process. Even with the enormous theoretical and experimental research work on these two osmolytes, various aspects of their underlying mechanisms still remain larg...

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Detalles Bibliográficos
Autores principales: Anand, D. Vijay, Meng, Zhenyu, Xia, Kelin, Mu, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297731/
https://www.ncbi.nlm.nih.gov/pubmed/32546801
http://dx.doi.org/10.1038/s41598-020-66710-6