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HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice

The molecular cause(s) for early onset heart failure in people living with HIV-1 infection (PLWH) remains poorly defined. Herein, longitudinal echocardiography was used to assess whether NOD.Cg-Prkdc(scid) Il2rgt(m1Wjl)/SzJ mice reconstituted with human hematopoietic stem cells (Hu-NSG mice) and inf...

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Detalles Bibliográficos
Autores principales: Dash, Prasanta K., Alomar, Fadhel A., Hackfort, Bryan T., Su, Hang, Conaway, Amy, Poluektova, Larisa Y, Gendelman, Howard E., Gorantla, Santhi, Bidasee, Keshore R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297773/
https://www.ncbi.nlm.nih.gov/pubmed/32546795
http://dx.doi.org/10.1038/s41598-020-65943-9