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Dual-Targeting Nanoparticle-Mediated Gene Therapy Strategy for Hepatocellular Carcinoma by Delivering Small Interfering RNA

As a gene therapy strategy, RNA interference (RNAi) offers tremendous tumor therapy potential. However, its therapeutic efficacy is restricted by its inferior ability for targeted delivery and cellular uptake of small interfering RNA (siRNA). This study sought to develop a dual-ligand nanoparticle (...

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Detalles Bibliográficos
Autores principales: Zheng, Qi Chang, Jiang, Shuai, Wu, Yu Zhe, Shang, Dan, Zhang, Yong, Hu, Shao Bo, Cheng, Xiang, Zhang, Chen, Sun, Ping, Gao, Yang, Song, Zi Fang, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297947/
https://www.ncbi.nlm.nih.gov/pubmed/32587849
http://dx.doi.org/10.3389/fbioe.2020.00512