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In vivo Screen Identifies Zdhhc2 as a Critical Regulator of Germinal Center B Cell Differentiation
Germinal center (GC) B cell differentiation is critical for the production of affinity-matured pathogen-specific antibodies, the dysregulation of which may lead to humoral immunodeficiency or autoimmunity. The development of an in vivo screening system for factors regulating GC B cell differentiatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297983/ https://www.ncbi.nlm.nih.gov/pubmed/32587588 http://dx.doi.org/10.3389/fimmu.2020.01025 |