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In vivo Screen Identifies Zdhhc2 as a Critical Regulator of Germinal Center B Cell Differentiation

Germinal center (GC) B cell differentiation is critical for the production of affinity-matured pathogen-specific antibodies, the dysregulation of which may lead to humoral immunodeficiency or autoimmunity. The development of an in vivo screening system for factors regulating GC B cell differentiatio...

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Detalles Bibliográficos
Autores principales: Zhao, Rongqing, Zhang, Huihui, Zhang, Yan, Li, Dan, Huang, Chuanxin, Li, Fubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297983/
https://www.ncbi.nlm.nih.gov/pubmed/32587588
http://dx.doi.org/10.3389/fimmu.2020.01025