Mesenchymal stem cells offer a drug-tolerant and immune-privileged niche to Mycobacterium tuberculosis

Anti-tuberculosis (TB) drugs, while being highly potent in vitro, require prolonged treatment to control Mycobacterium tuberculosis (Mtb) infections in vivo. We report here that mesenchymal stem cells (MSCs) shelter Mtb to help tolerate anti-TB drugs. MSCs readily take up Mtb and allow unabated myco...

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Detalles Bibliográficos
Autores principales: Jain, Neharika, Kalam, Haroon, Singh, Lakshyaveer, Sharma, Vartika, Kedia, Saurabh, Das, Prasenjit, Ahuja, Vineet, Kumar, Dhiraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297998/
https://www.ncbi.nlm.nih.gov/pubmed/32546788
http://dx.doi.org/10.1038/s41467-020-16877-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297998/
https://www.ncbi.nlm.nih.gov/pubmed/32546788
http://dx.doi.org/10.1038/s41467-020-16877-3

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