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Mesenchymal stem cells offer a drug-tolerant and immune-privileged niche to Mycobacterium tuberculosis
Anti-tuberculosis (TB) drugs, while being highly potent in vitro, require prolonged treatment to control Mycobacterium tuberculosis (Mtb) infections in vivo. We report here that mesenchymal stem cells (MSCs) shelter Mtb to help tolerate anti-TB drugs. MSCs readily take up Mtb and allow unabated myco...
Autores principales: | Jain, Neharika, Kalam, Haroon, Singh, Lakshyaveer, Sharma, Vartika, Kedia, Saurabh, Das, Prasenjit, Ahuja, Vineet, Kumar, Dhiraj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297998/ https://www.ncbi.nlm.nih.gov/pubmed/32546788 http://dx.doi.org/10.1038/s41467-020-16877-3 |
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