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Intratumoral immune activation with TLR4 agonist synergizes with effector T cells to eradicate established murine tumors

Effective T cell-based immunotherapy of solid malignancies requires intratumoral activity of cytotoxic T cells and induction of protective immune memory. A major obstacle to intratumoral trafficking and activation of vaccine-primed or adoptively transferred tumor-specific T cells is the immunosuppre...

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Detalles Bibliográficos
Autores principales:	Albershardt, Tina C., Leleux, Jardin, Parsons, Andrea J., Krull, Jordan E., Berglund, Peter, ter Meulen, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298055/ https://www.ncbi.nlm.nih.gov/pubmed/32579133 http://dx.doi.org/10.1038/s41541-020-0201-x

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