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High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes

Plasmodium falciparum is the causative agent of the deadliest human malaria. New molecules are needed that can specifically bind to erythrocytes that are infected with P. falciparum for diagnostic purposes, to disrupt host-parasite interactions, or to deliver chemotherapeutics. Aptamer technology ha...

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Detalles Bibliográficos
Autores principales: Oteng, Eugene K., Gu, Wenjuan, McKeague, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298056/
https://www.ncbi.nlm.nih.gov/pubmed/32546848
http://dx.doi.org/10.1038/s41598-020-66537-1