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AATF/Che-1—An RNA Binding Protein at the Nexus of DNA Damage Response and Ribosome Biogenesis

The DNA damage response (DDR) is a complex signaling network that is activated upon genotoxic stress. It determines cellular fate by either activating cell cycle arrest or initiating apoptosis and thereby ensures genomic stability. The Apoptosis Antagonizing Transcription Factor (AATF/Che-1), an RNA...

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Detalles Bibliográficos
Autores principales: Kaiser, Rainer W. J., Erber, Johanna, Höpker, Katja, Fabretti, Francesca, Müller, Roman-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298124/
https://www.ncbi.nlm.nih.gov/pubmed/32587828
http://dx.doi.org/10.3389/fonc.2020.00919