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Molecular mechanisms of thalidomide and its derivatives

Thalidomide, originally developed as a sedative drug, causes multiple defects due to severe teratogenicity, but it has been re-purposed for treating multiple myeloma, and derivatives such as lenalidomide and pomalidomide have been developed for treating blood cancers. Although the molecular mechanis...

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Detalles Bibliográficos
Autores principales: ITO, Takumi, HANDA, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298168/
https://www.ncbi.nlm.nih.gov/pubmed/32522938
http://dx.doi.org/10.2183/pjab.96.016