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Molecular mechanisms of thalidomide and its derivatives
Thalidomide, originally developed as a sedative drug, causes multiple defects due to severe teratogenicity, but it has been re-purposed for treating multiple myeloma, and derivatives such as lenalidomide and pomalidomide have been developed for treating blood cancers. Although the molecular mechanis...
Autores principales: | ITO, Takumi, HANDA, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298168/ https://www.ncbi.nlm.nih.gov/pubmed/32522938 http://dx.doi.org/10.2183/pjab.96.016 |
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