The Impact of the NOD2/CARD15 Variant (3020insC) and PSMA6 Polymorphism (-8C>G) on the Development and Outcome of Multiple Myeloma

INTRODUCTION: Multiple myeloma (MM) is a hematological malignancy characterized by genetic variety. The 3020insC variant of the NOD2/CARD15 gene results in the upregulation of proinflammatory cytokines. Chronic inflammation and abnormal function of the proteasome system may lead to MM development. T...

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Detalles Bibliográficos
Autores principales: Zmorzyński, S., Popek-Marciniec, S., Styk, W., Wojcierowska-Litwin, M., Korszeń-Pilecka, I., Szudy-Szczyrek, A., Chocholska, S., Hus, M., Filip, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298267/
https://www.ncbi.nlm.nih.gov/pubmed/32596371
http://dx.doi.org/10.1155/2020/7629456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298267/
https://www.ncbi.nlm.nih.gov/pubmed/32596371
http://dx.doi.org/10.1155/2020/7629456

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