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A rapid pyrosequencing assay for the molecular detection of influenza viruses with reduced baloxavir susceptibility due to PA/I38X amino acid substitutions

Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high‐risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following tr...

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Detalles Bibliográficos
Autores principales: Koszalka, Paulina, Farrukee, Rubaiyea, Mifsud, Edin, Vijaykrishna, Dhanasekaran, Hurt, Aeron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298287/
https://www.ncbi.nlm.nih.gov/pubmed/32045100
http://dx.doi.org/10.1111/irv.12725