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A rapid pyrosequencing assay for the molecular detection of influenza viruses with reduced baloxavir susceptibility due to PA/I38X amino acid substitutions
Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high‐risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following tr...
Autores principales: | Koszalka, Paulina, Farrukee, Rubaiyea, Mifsud, Edin, Vijaykrishna, Dhanasekaran, Hurt, Aeron C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298287/ https://www.ncbi.nlm.nih.gov/pubmed/32045100 http://dx.doi.org/10.1111/irv.12725 |
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