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Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity

Innate immune signaling via TLR4 plays critical roles in pathogenesis of metabolic disorders, but the contribution of different lipid species to metabolic disorders and inflammatory diseases is less clear. GM3 ganglioside in human serum is composed of a variety of fatty acids, including long‐chain (...

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Detalles Bibliográficos
Autores principales: Kanoh, Hirotaka, Nitta, Takahiro, Go, Shinji, Inamori, Kei‐ichiro, Veillon, Lucas, Nihei, Wataru, Fujii, Mayu, Kabayama, Kazuya, Shimoyama, Atsushi, Fukase, Koichi, Ohto, Umeharu, Shimizu, Toshiyuki, Watanabe, Taku, Shindo, Hiroki, Aoki, Sorama, Sato, Kenichi, Nagasaki, Mika, Yatomi, Yutaka, Komura, Naoko, Ando, Hiromune, Ishida, Hideharu, Kiso, Makoto, Natori, Yoshihiro, Yoshimura, Yuichi, Zonca, Asia, Cattaneo, Anna, Letizia, Marilena, Ciampa, Maria, Mauri, Laura, Prinetti, Alessandro, Sonnino, Sandro, Suzuki, Akemi, Inokuchi, Jin‐ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298289/
https://www.ncbi.nlm.nih.gov/pubmed/32378734
http://dx.doi.org/10.15252/embj.2019101732