Cargando…

RNA m(6)A methylation regulates sorafenib resistance in liver cancer through FOXO3‐mediated autophagy

N6‐methyladenosine (m(6)A) is an abundant nucleotide modification in mRNA, known to regulate mRNA stability, splicing, and translation, but it is unclear whether it is also has a physiological role in the intratumoral microenvironment and cancer drug resistance. Here, we find that METTL3, a primary...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Ziyou, Niu, Yi, Wan, Arabella, Chen, Dongshi, Liang, Heng, Chen, Xijun, Sun, Lei, Zhan, Siyue, Chen, Liutao, Cheng, Chao, Zhang, Xiaolei, Bu, Xianzhang, He, Weiling, Wan, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298296/
https://www.ncbi.nlm.nih.gov/pubmed/32368828
http://dx.doi.org/10.15252/embj.2019103181