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Dynamic properties of noise and Her6 levels are optimized by miR‐9, allowing the decoding of the Her6 oscillator

Noise is prevalent in biology and has been widely quantified using snapshot measurements. This static view obscures our understanding of dynamic noise properties and how these affect gene expression and cell state transitions. Using a CRISPR/Cas9 Zebrafish her6::Venus reporter combined with mathemat...

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Detalles Bibliográficos
Autores principales: Soto, Ximena, Biga, Veronica, Kursawe, Jochen, Lea, Robert, Doostdar, Parnian, Thomas, Riba, Papalopulu, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298297/
https://www.ncbi.nlm.nih.gov/pubmed/32395844
http://dx.doi.org/10.15252/embj.2019103558