Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome

Primary cilia are antenna‐like organelles on the surface of most mammalian cells that receive sonic hedgehog (Shh) signaling in embryogenesis and carcinogenesis. Cellular cholesterol functions as a direct activator of a seven‐transmembrane oncoprotein called Smoothened (Smo) and thereby induces Smo...

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Detalles Bibliográficos
Autores principales: Miyamoto, Tatsuo, Hosoba, Kosuke, Itabashi, Takeshi, Iwane, Atsuko H, Akutsu, Silvia Natsuko, Ochiai, Hiroshi, Saito, Yumiko, Yamamoto, Takashi, Matsuura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298307/
https://www.ncbi.nlm.nih.gov/pubmed/32368833
http://dx.doi.org/10.15252/embj.2019103499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298307/
https://www.ncbi.nlm.nih.gov/pubmed/32368833
http://dx.doi.org/10.15252/embj.2019103499

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