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Quantum mechanics and 3D-QSAR studies on thienopyridine analogues: inhibitors of IKKβ
Inhibitor of kappa B kinase subunit β (IKKβ) is a main regulator of nuclear factor kappa B (NF-κB) and has received considerable attention as an attractive therapeutic target for the treatment of lung cancer or other inflammatory disease. A group of diversified thienopyridine derivatives exhibited a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298411/ https://www.ncbi.nlm.nih.gov/pubmed/32566780 http://dx.doi.org/10.1016/j.heliyon.2020.e04125 |