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Calcium-mineralized polypeptide nanoparticle for intracellular drug delivery in osteosarcoma chemotherapy
The acidic microenvironments of tumor tissue and cells provide an opportunity for the development of pH-responsive drug delivery systems in cancer therapy. In this work, we designed a calcium carbonate (CaCO(3))-core-crosslinked nanoparticle of methoxy poly(ethylene glycol)-block-poly(l-glutamic aci...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298657/ https://www.ncbi.nlm.nih.gov/pubmed/32596554 http://dx.doi.org/10.1016/j.bioactmat.2020.04.010 |