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Calcium-mineralized polypeptide nanoparticle for intracellular drug delivery in osteosarcoma chemotherapy

The acidic microenvironments of tumor tissue and cells provide an opportunity for the development of pH-responsive drug delivery systems in cancer therapy. In this work, we designed a calcium carbonate (CaCO(3))-core-crosslinked nanoparticle of methoxy poly(ethylene glycol)-block-poly(l-glutamic aci...

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Detalles Bibliográficos
Autores principales: Li, Ke, Li, Di, Zhao, Li, Chang, Yonghe, Zhang, Yi, Cui, Yan, Zhang, Zhiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298657/
https://www.ncbi.nlm.nih.gov/pubmed/32596554
http://dx.doi.org/10.1016/j.bioactmat.2020.04.010