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Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients

BACKGROUND: Cerebral metabolic rate of oxygen (CMRO(2)), a measure of global oxygen metabolism, reflects resting cellular activity. The mechanisms underlying fatigue and cognitive dysfunction in multiple sclerosis (MS) remain unknown. If fatigue indeed reflects ongoing autoimmune activity and cortic...

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Detalles Bibliográficos
Autores principales: West, Kl., Sivakolundu, Dk., Maruthy, Gb., Zuppichini, Md., Liu, P., Thomas, Bp., Spence, Js., Lu, H., Okuda, Dt., Rypma, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298673/
https://www.ncbi.nlm.nih.gov/pubmed/32544855
http://dx.doi.org/10.1016/j.nicl.2020.102281