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Evaluation of T-activated proteins as recall antigens to monitor Epstein–Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting

BACKGROUND: Pools of overlapping synthetic peptides are routinely used for ex vivo monitoring of antigen-specific T-cell responses. However, it is rather unlikely that these peptides match those resulting from naturally processed antigens. T-activated proteins have been described as immunogenic and...

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Detalles Bibliográficos
Autores principales: Körber, Nina, Behrends, Uta, Protzer, Ulrike, Bauer, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298696/
https://www.ncbi.nlm.nih.gov/pubmed/32552697
http://dx.doi.org/10.1186/s12967-020-02385-x