Cargando…
Evaluation of T-activated proteins as recall antigens to monitor Epstein–Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting
BACKGROUND: Pools of overlapping synthetic peptides are routinely used for ex vivo monitoring of antigen-specific T-cell responses. However, it is rather unlikely that these peptides match those resulting from naturally processed antigens. T-activated proteins have been described as immunogenic and...
Autores principales: | Körber, Nina, Behrends, Uta, Protzer, Ulrike, Bauer, Tanja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298696/ https://www.ncbi.nlm.nih.gov/pubmed/32552697 http://dx.doi.org/10.1186/s12967-020-02385-x |
Ejemplares similares
-
Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring
por: Körber, Nina, et al.
Publicado: (2016) -
Immunoinformatic Analysis Reveals Antigenic Heterogeneity of Epstein-Barr Virus Is Immune-Driven
por: Cirac, Ana, et al.
Publicado: (2021) -
Immunodominance of Lytic Cycle Antigens in Epstein-Barr Virus-Specific CD4+ T Cell Preparations for Therapy
por: Adhikary, Dinesh, et al.
Publicado: (2007) -
Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins
por: Adhikary, Dinesh, et al.
Publicado: (2006) -
Cytomegalovirus and Epstein-Barr Virus in Breast Cancer
por: Richardson, Ann K., et al.
Publicado: (2015)