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Risk1, a Phosphatidylinositol 3-Kinase Effector, Promotes Rickettsia typhi Intracellular Survival

To establish a habitable intracellular niche, various pathogenic bacteria secrete effectors that target intracellular trafficking and modulate phosphoinositide (PI) metabolism. Murine typhus, caused by the obligate intracellular bacterium Rickettsia typhi, remains a severe disease in humans. However...

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Detalles Bibliográficos
Autores principales: Voss, Oliver H., Gillespie, Joseph J., Lehman, Stephanie S., Rennoll, Sherri A., Beier-Sexton, Magda, Rahman, M. Sayeedur, Azad, Abdu F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298712/
https://www.ncbi.nlm.nih.gov/pubmed/32546622
http://dx.doi.org/10.1128/mBio.00820-20