Genome engineering of induced pluripotent stem cells to manufacture natural killer cell therapies

Natural killer (NK) cells play a crucial role in host immunity by detecting cells that downregulate MHC class I presentation and upregulate stress ligands, as commonly seen in cancers. Current NK therapies using primary NK cells are prone to manufacturing issues related to expansion and storage. Alt...

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Detalles Bibliográficos
Autores principales: Shankar, Keerthana, Capitini, Christian M., Saha, Krishanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298853/
https://www.ncbi.nlm.nih.gov/pubmed/32546200
http://dx.doi.org/10.1186/s13287-020-01741-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298853/
https://www.ncbi.nlm.nih.gov/pubmed/32546200
http://dx.doi.org/10.1186/s13287-020-01741-4

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