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Alpha‐lipoic acid downregulates TRPV1 receptor via NF‐κB and attenuates neuropathic pain in rats with diabetes

AIMS: Painful diabetic neuropathy (PDN) is a refractory complication of diabetes. The study aimed to investigate the role of α‐lipoic acid (ALA) on the regulation of transient receptor potential vanilloid‐1 (TRPV1) in dorsal root ganglion (DRG) neurons of rats with diabetes. METHODS: Whole‐cell patc...

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Detalles Bibliográficos
Autores principales: Zhang, Bing‐Yu, Zhang, Yi‐Lian, Sun, Qian, Zhang, Ping‐An, Wang, Xi‐Xi, Xu, Guang‐Yin, Hu, Ji, Zhang, Hong‐Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298987/
https://www.ncbi.nlm.nih.gov/pubmed/32175676
http://dx.doi.org/10.1111/cns.13303