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FADS1 (Fatty Acid Desaturase 1) Genotype Associates With Aortic Valve FADS mRNA Expression, Fatty Acid Content and Calcification

Aortic stenosis (AS) contributes to cardiovascular mortality and morbidity but disease mechanisms remain largely unknown. Recent evidence associates a single nucleotide polymorphism rs174547 within the FADS1 gene, encoding FADS1 (fatty acid desaturase 1), with risk of several cardiovascular outcomes...

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Detalles Bibliográficos
Autores principales: Plunde, Oscar, Larsson, Susanna C., Artiach, Gonzalo, Thanassoulis, George, Carracedo, Miguel, Franco-Cereceda, Anders, Eriksson, Per, Bäck, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299231/
https://www.ncbi.nlm.nih.gov/pubmed/32397743
http://dx.doi.org/10.1161/CIRCGEN.119.002710