Hydrated electrons induce the formation of interstrand cross-links in DNA modified by cisplatin adducts

Double-stranded oligonucleotides containing cisplatin adducts, with and without a mismatched region, were exposed to hydrated electrons generated by gamma-rays. Gel electrophoresis analysis demonstrates the formation of cisplatin-interstrand crosslinks from the cisplatin-intrastrand species. The rat...

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Detalles Bibliográficos
Autores principales: Behmand, B, Noronha, A M, Wilds, C J, Marignier, J-L, Mostafavi, M, Wagner, J R, Hunting, D J, Sanche, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Regular Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299263/
https://www.ncbi.nlm.nih.gov/pubmed/32211848
http://dx.doi.org/10.1093/jrr/rraa014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299263/
https://www.ncbi.nlm.nih.gov/pubmed/32211848
http://dx.doi.org/10.1093/jrr/rraa014

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