Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

Antibodies targeting the spike protein of SARS-CoV-2 present a promising approach to combat the COVID19 pandemic; however, concerns remain that mutations can yield antibody resistance. We investigate the development of resistance against four antibodies to the spike protein that potently neutralize...

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Detalles Bibliográficos
Autores principales: Baum, Alina, Fulton, Benjamin O., Wloga, Elzbieta, Copin, Richard, Pascal, Kristen E., Russo, Vincenzo, Giordano, Stephanie, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Atwal, Gurinder S., Murphy, Andrew J., Stahl, Neil, Yancopoulos, George D., Kyratsous, Christos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299283/
https://www.ncbi.nlm.nih.gov/pubmed/32540904
http://dx.doi.org/10.1126/science.abd0831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299283/
https://www.ncbi.nlm.nih.gov/pubmed/32540904
http://dx.doi.org/10.1126/science.abd0831

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