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Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

Neutralizing antibodies have become an important tool in treating infectious diseases. Recently, two separate approaches yielded successful antibody treatments for Ebola—one from genetically humanized mice and the other from a human survivor. Here, we describe parallel efforts using both humanized m...

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Detalles Bibliográficos
Autores principales: Hansen, Johanna, Baum, Alina, Pascal, Kristen E., Russo, Vincenzo, Giordano, Stephanie, Wloga, Elzbieta, Fulton, Benjamin O., Yan, Ying, Koon, Katrina, Patel, Krunal, Chung, Kyung Min, Hermann, Aynur, Ullman, Erica, Cruz, Jonathan, Rafique, Ashique, Huang, Tammy, Fairhurst, Jeanette, Libertiny, Christen, Malbec, Marine, Lee, Wen-yi, Welsh, Richard, Farr, Glen, Pennington, Seth, Deshpande, Dipali, Cheng, Jemmie, Watty, Anke, Bouffard, Pascal, Babb, Robert, Levenkova, Natasha, Chen, Calvin, Zhang, Bojie, Romero Hernandez, Annabel, Saotome, Kei, Zhou, Yi, Franklin, Matthew, Sivapalasingam, Sumathi, Lye, David Chien, Weston, Stuart, Logue, James, Haupt, Robert, Frieman, Matthew, Chen, Gang, Olson, William, Murphy, Andrew J., Stahl, Neil, Yancopoulos, George D., Kyratsous, Christos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299284/
https://www.ncbi.nlm.nih.gov/pubmed/32540901
http://dx.doi.org/10.1126/science.abd0827