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Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis

Programmed cellular responses to cycling ovarian-derived steroid hormones are central to normal endometrial function. Abnormalities therein, as in the estrogen-dependent, progesterone-“resistant” disorder, endometriosis, predispose to infertility and poor pregnancy outcomes. The endometrial stromal...

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Detalles Bibliográficos
Autores principales: Houshdaran, Sahar, Oke, Ashwini B., Fung, Jennifer C., Vo, Kim Chi, Nezhat, Camran, Giudice, Linda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299312/
https://www.ncbi.nlm.nih.gov/pubmed/32555663
http://dx.doi.org/10.1371/journal.pgen.1008601