Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

Mitochondrial membrane dynamics is a cellular rheostat that relates metabolic function and organelle morphology. Using an in vitro reconstitution system, we describe a mechanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two forms of Opa1. We found that the long-form of...

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Detalles Bibliográficos
Autores principales: Ge, Yifan, Shi, Xiaojun, Boopathy, Sivakumar, McDonald, Julie, Smith, Adam W, Chao, Luke H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299343/
https://www.ncbi.nlm.nih.gov/pubmed/31922487
http://dx.doi.org/10.7554/eLife.50973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299343/
https://www.ncbi.nlm.nih.gov/pubmed/31922487
http://dx.doi.org/10.7554/eLife.50973

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