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Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane
Mitochondrial membrane dynamics is a cellular rheostat that relates metabolic function and organelle morphology. Using an in vitro reconstitution system, we describe a mechanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two forms of Opa1. We found that the long-form of...
Autores principales: | Ge, Yifan, Shi, Xiaojun, Boopathy, Sivakumar, McDonald, Julie, Smith, Adam W, Chao, Luke H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299343/ https://www.ncbi.nlm.nih.gov/pubmed/31922487 http://dx.doi.org/10.7554/eLife.50973 |
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