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Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in Drosophila

Like tissues of many organisms, Drosophila imaginal discs lose the ability to regenerate as they mature. This loss of regenerative capacity coincides with reduced damage-responsive expression of multiple genes needed for regeneration. We previously showed that two such genes, wg and Wnt6, are regula...

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Detalles Bibliográficos
Autores principales: Harris, Robin E, Stinchfield, Michael J, Nystrom, Spencer L, McKay, Daniel J, Hariharan, Iswar K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299344/
https://www.ncbi.nlm.nih.gov/pubmed/32490812
http://dx.doi.org/10.7554/eLife.58305