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Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner
Renal dysplasia, the major cause of childhood renal failure, is characterized by defective branching morphogenesis and nephrogenesis. Beta-catenin, a transcription factor and cell adhesion molecule, is markedly increased in the nucleus of kidney cells in human renal dysplasia and contributes to its...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299361/ https://www.ncbi.nlm.nih.gov/pubmed/32555682 http://dx.doi.org/10.1371/journal.pone.0234375 |