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Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner

Renal dysplasia, the major cause of childhood renal failure, is characterized by defective branching morphogenesis and nephrogenesis. Beta-catenin, a transcription factor and cell adhesion molecule, is markedly increased in the nucleus of kidney cells in human renal dysplasia and contributes to its...

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Detalles Bibliográficos
Autores principales:	Cunanan, Joanna, Deacon, Erin, Cunanan, Kristina, Yang, Zifan, Ask, Antje, Morikawa, Lily, Todorova, Ekaterina, Bridgewater, Darren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299361/ https://www.ncbi.nlm.nih.gov/pubmed/32555682 http://dx.doi.org/10.1371/journal.pone.0234375

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