Identification of functionally connected multi-omic biomarkers for Alzheimer’s disease using modularity-constrained Lasso

Large-scale genome wide association studies (GWASs) have led to discovery of many genetic risk factors in Alzheimer’s disease (AD), such as APOE, TOMM40 and CLU. Despite the significant progress, it remains a major challenge to functionally validate these genetic findings and translate them into tar...

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Detalles Bibliográficos
Autores principales: Xie, Linhui, Varathan, Pradeep, Nho, Kwangsik, Saykin, Andrew J., Salama, Paul, Yan, Jingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299377/
https://www.ncbi.nlm.nih.gov/pubmed/32555747
http://dx.doi.org/10.1371/journal.pone.0234748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299377/
https://www.ncbi.nlm.nih.gov/pubmed/32555747
http://dx.doi.org/10.1371/journal.pone.0234748

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