NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture

Sepsis is characterized by organ dysfunction due to a dysregulated immune response to infection. Currently, no effective treatment for sepsis exists. Platelets are recognized as mediators of the immune response and may be a potential therapeutic target for the treatment of sepsis. We previously demo...

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Detalles Bibliográficos
Autores principales: Cornelius, Denise C., Travis, Olivia K., Tramel, Robert W., Borges-Rodriguez, Marivee, Baik, Cedar H., Greer, Mallory, Giachelli, Chelsea A., Tardo, Geilda A., Williams, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299389/
https://www.ncbi.nlm.nih.gov/pubmed/32555710
http://dx.doi.org/10.1371/journal.pone.0234039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299389/
https://www.ncbi.nlm.nih.gov/pubmed/32555710
http://dx.doi.org/10.1371/journal.pone.0234039

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