Cargando…

NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture

Sepsis is characterized by organ dysfunction due to a dysregulated immune response to infection. Currently, no effective treatment for sepsis exists. Platelets are recognized as mediators of the immune response and may be a potential therapeutic target for the treatment of sepsis. We previously demo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cornelius, Denise C., Travis, Olivia K., Tramel, Robert W., Borges-Rodriguez, Marivee, Baik, Cedar H., Greer, Mallory, Giachelli, Chelsea A., Tardo, Geilda A., Williams, Jan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299389/ https://www.ncbi.nlm.nih.gov/pubmed/32555710 http://dx.doi.org/10.1371/journal.pone.0234039

Ejemplares similares

Platelet Inhibition Prevents NLRP3 Inflammasome Activation and Sepsis-Induced Kidney Injury
por: Borges-Rodriguez, Marivee, et al.
Publicado: (2021)

NLRP3 inflammasome activation in platelets in response to sepsis
por: Cornelius, Denise C., et al.
Publicado: (2019)

Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis
por: Su, Jingqian, et al.
Publicado: (2023)

Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture
por: Ruiz, Stéphanie, et al.
Publicado: (2016)

Western diet enhances hepatic inflammation in mice exposed to cecal ligation and puncture
por: Rivera, Chantal A, et al.
Publicado: (2010)

Protective role of autophagy in mouse cecal ligation and puncture-induced sepsis model
por: Takahashi, W, et al.
Publicado: (2013)

Protective Effect of Citrulline on the Hearts of Rats with Sepsis Induced by Cecal Ligation and Puncture
por: Zhou, Ji-qiu, et al.
Publicado: (2018)

5-HT Drives Mortality in Sepsis Induced by Cecal Ligation and Puncture in Mice
por: Zhang, Jingyao, et al.
Publicado: (2017)

Effects of sesamol against acute kidney injury in cecal-ligation-and-puncture-treated rats
por: Chien, S, et al.
Publicado: (2012)

Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture
por: Wu, Shao-Chun, et al.
Publicado: (2013)

Kinetics and protective role of autophagy in a mouse cecal ligation and puncture-induced sepsis
por: Takahashi, Waka, et al.
Publicado: (2013)

Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis
por: OLGUNER, ÇIMEN GÜLBEN, et al.
Publicado: (2013)

Cecal Ligation and Puncture Results in Long-Term Central Nervous System Myeloid Inflammation
por: Singer, Benjamin H., et al.
Publicado: (2016)

Lactate as a Potential Biomarker of Sepsis in a Rat Cecal Ligation and Puncture Model
por: Zhai, Xiaozhu, et al.
Publicado: (2018)

Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats
por: Sun, Guodong, et al.
Publicado: (2017)

Analysis of blood culture in a rat model of cecal ligation and puncture induced sepsis
por: Vaittinada Ayar, Prabakar, et al.
Publicado: (2020)

Inhibitory Activities of Rare Ginsenoside Rg4 on Cecal Ligation and Puncture-Induced Sepsis
por: Kim, Go Oun, et al.
Publicado: (2022)

Protective effects of the combination of sodium ferulate and oxymatrine on cecal ligation and puncture-induced sepsis in mice
por: XU, MENGXIN, et al.
Publicado: (2014)

Possible involvement of rho kinase 1 (rock 1) in cecal ligation and puncture-induced sepsis
por: Cinel, I, et al.
Publicado: (2005)

Effects of phloretin on oxidative and inflammatory reaction in rat model of cecal ligation and puncture induced sepsis
por: Aliomrani, Mehdi, et al.
Publicado: (2016)

Shorter Duration of Post-Operative Antibiotics for Cecal Ligation and Puncture Does Not Increase Inflammation or Mortality
por: Iskander, Kendra N., et al.
Publicado: (2016)

Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis
por: Mai, Safiah H. C., et al.
Publicado: (2018)

Influence of autophagy on acute kidney injury in a murine cecal ligation and puncture sepsis model
por: Sunahara, Satoshi, et al.
Publicado: (2018)

The clinical and immunological performance of 28 days survival model of cecal ligation and puncture in humanized mice
por: Laudanski, Krzysztof, et al.
Publicado: (2017)

Sepsis Strengthens Antagonistic Actions of Neostigmine on Rocuronium in a Rat Model of Cecal Ligation and Puncture
por: Wu, Jin, et al.
Publicado: (2016)

Circular RNA expression in the lungs of a mouse model of sepsis induced by cecal ligation and puncture
por: Yuan, Caiyun, et al.
Publicado: (2020)

Nordihydroguaiaretic acid reduces secondary organ injury in septic rats after cecal ligation and puncture
por: Zubrow, Michael E., et al.
Publicado: (2020)

Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice
por: O'Riordan, Caroline E., et al.
Publicado: (2019)

Contributory Role of BLT2 in the Production of Proinflammatory Cytokines in Cecal Ligation and Puncture-Induced Sepsis
por: Park, Donghwan, et al.
Publicado: (2021)

Myrrh Inhibits LPS-Induced Inflammatory Response and Protects from Cecal Ligation and Puncture-Induced Sepsis
por: Kim, Min-Sun, et al.
Publicado: (2012)

Increased survival after a cecal ligation and puncture-induced sepsis in mice consuming oleic acid
por: de Moraes, IM, et al.
Publicado: (2010)

Involvement of thrombopoietin in the development of organ injury in a mouse model of cecal ligation and puncture-induced sepsis
por: Greco, E, et al.
Publicado: (2012)

Effects of crystalloids and colloids on liver and intestine microcirculation and function in cecal ligation and puncture induced septic rodents
por: Schick, Martin Alexander, et al.
Publicado: (2012)

Intraperitoneal adipose tissue is strongly related to survival rate in a mouse cecal ligation and puncture model
por: Niiyama, Shuhei, et al.
Publicado: (2016)

Non-cultured dermal-derived mesenchymal cells attenuate sepsis induced by cecal ligation and puncture in mice
por: Wang, Yu, et al.
Publicado: (2015)

Effect of Electroacupuncture at Zusanli (ST36) on Sepsis Induced by Cecal Ligation Puncture and Its Relevance to Spleen
por: Xie, Dong-ping, et al.
Publicado: (2020)

Evaluation of 2 Rat Models for Sepsis Developed by Improved Cecal Ligation/Puncture or Feces Intraperitoneal-Injection
por: Fang, Hui, et al.
Publicado: (2020)

sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions
por: Chen, Zhihui, et al.
Publicado: (2020)

Multi-Organ Transcriptome Dynamics in a Mouse Model of Cecal Ligation and Puncture-Induced Polymicrobial Sepsis
por: Rumienczyk, Izabela, et al.
Publicado: (2021)

The Effect of Bortezomib on Expression of Inflammatory Cytokines and Survival in a Murine Sepsis Model Induced by Cecal Ligation and Puncture
por: Han, Sang Hoon, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qn9r39mk1lsi06aa1fh0pi5rv3