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Detecting differential alternative splicing events in scRNA-seq with or without Unique Molecular Identifiers

The emergence of single-cell RNA-seq (scRNA-seq) technology has made it possible to measure gene expression variations at cellular level. This breakthrough enables the investigation of a wider range of problems including analysis of splicing heterogeneity among individual cells. However, compared to...

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Detalles Bibliográficos
Autores principales: Hu, Yu, Wang, Kai, Li, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299405/
https://www.ncbi.nlm.nih.gov/pubmed/32502143
http://dx.doi.org/10.1371/journal.pcbi.1007925