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miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma

Despite significant development of melanoma therapies, death rates remain high. MicroRNAs, controlling posttranscriptionally gene expression, play role in development of resistance to BRAF inhibitors. The aim of the study was to assess the role of miR-410-3p in response to vemurafenib–BRAF inhibitor...

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Detalles Bibliográficos
Autores principales: Grzywa, Tomasz M., Klicka, Klaudia, Paskal, Wiktor, Dudkiewicz, Julia, Wejman, Jarosław, Pyzlak, Michał, Włodarski, Paweł K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299409/
https://www.ncbi.nlm.nih.gov/pubmed/32555626
http://dx.doi.org/10.1371/journal.pone.0234707